PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30108443-8	2018	Meanwhile, multiplex PCR designed to detect the ampicillin and amoxicillin-clavulanic acid resistant E. coli isolates revealed positive amplification of 516 bp fragments specific for BlaTEM gene with all the resistant strains to ampicillin and amoxicillin-clavulanic acid.	Ampicillin	48-58	TEM-1 beta-lactamase	Escherichia coli	183-189	
30108443-8	2018	Meanwhile, multiplex PCR designed to detect the ampicillin and amoxicillin-clavulanic acid resistant E. coli isolates revealed positive amplification of 516 bp fragments specific for BlaTEM gene with all the resistant strains to ampicillin and amoxicillin-clavulanic acid.	Ampicillin	229-239	TEM-1 beta-lactamase	Escherichia coli	183-189	
15713611-5	2005	The resistance of EIEC O164 to ampicillin was found to be due to the presence of TEM-1 beta-lactamase.	Ampicillin	31-41	TEM-1 beta-lactamase	Escherichia coli	81-101	
21393132-2	2011	This study examined the distribution of the closely related blaTEM transposons Tn1, Tn2 and Tn3, or blaTEM-containing fragments of them, in ampicillin-resistant human commensal Escherichia coli isolates.	Ampicillin	140-150	TEM-1 beta-lactamase	Escherichia coli	60-66	
21393132-2	2011	This study examined the distribution of the closely related blaTEM transposons Tn1, Tn2 and Tn3, or blaTEM-containing fragments of them, in ampicillin-resistant human commensal Escherichia coli isolates.	Ampicillin	140-150	TEM-1 beta-lactamase	Escherichia coli	100-106	
21393132-7	2011	RESULTS: Of 25 ampicillin-resistant E. coli strains recovered from the faecal flora of healthy humans that carried the blaTEM gene, 15 carried a complete copy of Tn2 or a Tn2 variant; one was interrupted by IS4.	Ampicillin	15-25	TEM-1 beta-lactamase	Escherichia coli	119-125	
18611568-4	1994	Identification of the beta-lactamases produced by the ampicillin-resistant isolates demonstrated that the TEM-1 beta-lactamase predominated particularly in E. coli where it was identified in 86% of isolates.	Ampicillin	54-64	TEM-1 beta-lactamase	Escherichia coli	106-126	
8067751-1	1994	The mutation of Arg-244 to Ser (Arg-244-->Ser mutation) in the TEM-1 beta-lactamase has been shown to produce resistance to inactivation by clavulanate in the mutant enzyme and resistance to ampicillin plus clavulanate in a strain of Escherichia coli producing this enzyme.	Ampicillin	194-204	TEM-1 beta-lactamase	Escherichia coli	66-86	
8432315-2	1993	The TEM-1 beta-lactamase was found to be most prevalent occurring in 88.2% of ampicillin-resistant isolates tested.	Ampicillin	78-88	TEM-1 beta-lactamase	Escherichia coli	4-24	
2690414-6	1989	The one exception is the TEM-1 beta-lactamase which is found wherever transferable ampicillin resistance emerges and accounts for over 50% of all plasmid encoded ampicillin resistance.	Ampicillin	83-93	TEM-1 beta-lactamase	Escherichia coli	25-45	
2190970-6	1990	Further study indicated that the ampicillin resistance gene probe reacted with the gene for TEM-1 beta-lactamase and that the gene probe for sulphonamide resistance reacted with the gene for type II dihydropteroate synthase.	Ampicillin	33-43	TEM-1 beta-lactamase	Escherichia coli	92-112	
2182386-1	1990	During an outbreak of infection with ampicillin-resistant, TEM-1 beta-lactamase-producing Escherichia coli serotype O15, some strains were noted to differ from the majority in that they showed reduced susceptibility to amoxycillin/clavulanic acid (Augmentin), ureidopenicillins and first generation cephalosporins and produced increased amounts of beta-lactamase.	Ampicillin	37-47	TEM-1 beta-lactamase	Escherichia coli	59-79	
2690414-6	1989	The one exception is the TEM-1 beta-lactamase which is found wherever transferable ampicillin resistance emerges and accounts for over 50% of all plasmid encoded ampicillin resistance.	Ampicillin	162-172	TEM-1 beta-lactamase	Escherichia coli	25-45	
3516962-0	1986	Behaviour of TEM-1 beta-lactamase as a resistance mechanism to ampicillin, mezlocillin and azlocillin in Escherichia coli.	Ampicillin	63-73	TEM-1 beta-lactamase	Escherichia coli	13-33	
3516962-6	1986	Extracted TEM-1 beta-lactamase hydrolysed high concentrations of mezlocillin more rapidly than ampicillin and azlocillin; however, mezlocillin was calculated to be the weakest substrate at the low concentrations which are likely to be obtainable in the bacterial cell.	Ampicillin	95-105	TEM-1 beta-lactamase	Escherichia coli	10-30