PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32878784-4 2020 RESULTS: CEP1347 selectively inhibited the growth of retinoblastoma cell lines expressing murine double minute 4 (MDM4), a P53 inhibitor. 3,9-bis((ethylthio)methyl)-K-252a 9-16 transformation related protein 53, pseudogene Mus musculus 123-126 32878784-5 2020 Furthermore, CEP1347 reduced the expression of MDM4 and activated the P53 pathway in MDM4-expressing retinoblastoma cells, which was required for the inhibition of their growth by CEP1347. 3,9-bis((ethylthio)methyl)-K-252a 13-20 transformation related protein 53, pseudogene Mus musculus 70-73 32878784-5 2020 Furthermore, CEP1347 reduced the expression of MDM4 and activated the P53 pathway in MDM4-expressing retinoblastoma cells, which was required for the inhibition of their growth by CEP1347. 3,9-bis((ethylthio)methyl)-K-252a 180-187 transformation related protein 53, pseudogene Mus musculus 70-73 32878784-6 2020 CONCLUSION: We propose CEP1347 as a promising candidate for the treatment of retinoblastomas, where functional inactivation of P53 as a result of MDM4 activation is reportedly common. 3,9-bis((ethylthio)methyl)-K-252a 23-30 transformation related protein 53, pseudogene Mus musculus 127-130