PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29084209-6	2018	Pretreatment with the ROS scavenger N-acetyl-L-cysteine, the ERK1/2 inhibitor UO126, or ERK1/2 siRNA knockdown blocked the H2O2-induced shift of MLK3, while MLK3 inhibition with Cep1347 did not.	3,9-bis((ethylthio)methyl)-K-252a	178-185	mitogen-activated protein kinase kinase kinase 11	Homo sapiens	145-149	
33298586-8	2021	Knockdown of MAP3K11 reduced cell survival and pharmacologic inhibition of MAP3K11 with CEP-1347 in combination with enzalutamide resulted in a dramatic increase in cell death.	3,9-bis((ethylthio)methyl)-K-252a	88-96	mitogen-activated protein kinase kinase kinase 11	Homo sapiens	13-20	
33298586-8	2021	Knockdown of MAP3K11 reduced cell survival and pharmacologic inhibition of MAP3K11 with CEP-1347 in combination with enzalutamide resulted in a dramatic increase in cell death.	3,9-bis((ethylthio)methyl)-K-252a	88-96	mitogen-activated protein kinase kinase kinase 11	Homo sapiens	75-82	
15019567-12	2004	These studies show that inhibition of the MLK 3/JNK pathway attenuates MPP(+)-mediated SH-SY5Y cell death in culture and supports the mechanism of action of CEP-1347 as an MLK family inhibitor.	3,9-bis((ethylthio)methyl)-K-252a	157-165	mitogen-activated protein kinase kinase kinase 11	Homo sapiens	42-47