PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30781671-6	2019	Zerumbone has shown its anti-cancer effects by causing significant suppression of proliferation, survival, angiogenesis, invasion, and metastasis through the molecular modulation of different pathways such as NF-kappaB, Akt, and IL-6/JAK2/STAT3 (interleukin-6/janus kinase-2/signal transducer and activator of transcription 3) and their downstream target proteins.	zerumbone	0-9	Janus kinase 2	Homo sapiens	234-238	
30781671-6	2019	Zerumbone has shown its anti-cancer effects by causing significant suppression of proliferation, survival, angiogenesis, invasion, and metastasis through the molecular modulation of different pathways such as NF-kappaB, Akt, and IL-6/JAK2/STAT3 (interleukin-6/janus kinase-2/signal transducer and activator of transcription 3) and their downstream target proteins.	zerumbone	0-9	Janus kinase 2	Homo sapiens	260-274	
25243457-0	2015	Zerumbone inhibits growth of hormone refractory prostate cancer cells by inhibiting JAK2/STAT3 pathway and increases paclitaxel sensitivity.	zerumbone	0-9	Janus kinase 2	Homo sapiens	84-88	
25243457-6	2015	Zerumbone selectively inhibited JAK2 in both DU145 and PC3 cells.	zerumbone	0-9	Janus kinase 2	Homo sapiens	32-36	
25243457-11	2015	Further preclinical study might reveal the potential use of zerumbone as a chemotherapeutic agent for hormone refractory prostate cancer where IL-6/JAK2/STAT3 signaling is aberrantly active and may be combined with PTX.	zerumbone	60-69	Janus kinase 2	Homo sapiens	148-152	
28602099-11	2018	Ionizing radiation augmented and zerumbone pretreatment reduced the expression of Jak2 and Stat3, which are involved in DNA damage repair signaling.	zerumbone	33-42	Janus kinase 2	Homo sapiens	82-86