PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35436748-2 2022 Our effort to identify selective, CNS-penetrant Nav1.7 blockers with oral activity, improved selectivity, good drug-like properties, and safety led to the discovery of 2-substituted quinolines and quinolones as potent small molecule Nav1.7 blockers. Quinolines 182-192 sodium voltage-gated channel alpha subunit 9 Homo sapiens 48-54 35436748-2 2022 Our effort to identify selective, CNS-penetrant Nav1.7 blockers with oral activity, improved selectivity, good drug-like properties, and safety led to the discovery of 2-substituted quinolines and quinolones as potent small molecule Nav1.7 blockers. Quinolines 182-192 sodium voltage-gated channel alpha subunit 9 Homo sapiens 233-239