PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25159194-4	2015	Oxidative metabolism of pomalidomide was predominately mediated by CYP1A2 and CYP3A4, and pomalidomide was shown to be a P-gp substrate.	pomalidomide	24-36	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	78-84	
25159194-9	2015	Pomalidomide dose should be reduced by 50% if co-administered with strong CYP1A2 inhibitors and strong CYP3A/P-gp inhibitors.	pomalidomide	0-12	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	103-108	
24086951-4	2013	Pomalidomide is extensively metabolized, mainly by the cytochrome P450 3A4 and 1A2 pathways.	pomalidomide	0-12	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	55-82	
29762875-2	2018	In vitro data showed that pomalidomide is a substrate of multiple cytochrome P450 (CYP) isozymes and that its oxidative metabolism is mediated primarily by CYP1A2 and CYP3A4, with minor contributions from CYP2C19 and CYP2D6.	pomalidomide	26-38	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	167-173