PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25596735-4 2015 Carnosic acid induced down-regulation of c-FLIP and Bcl-2 expression at the post-translational levels, and the over-expression of c-FLIP and Bcl-2 markedly blocked carnosic acid-induced TRAIL sensitization. salvin 164-177 TNF superfamily member 10 Homo sapiens 186-191 25596735-0 2015 Carnosic acid sensitized TRAIL-mediated apoptosis through down-regulation of c-FLIP and Bcl-2 expression at the post translational levels and CHOP-dependent up-regulation of DR5, Bim, and PUMA expression in human carcinoma caki cells. salvin 0-13 TNF superfamily member 10 Homo sapiens 25-30 25596735-2 2015 In this study, we examined whether carnosic acid could sensitize TRAIL-mediated apoptosis in human renal carcinoma Caki cells. salvin 35-48 TNF superfamily member 10 Homo sapiens 65-70 25596735-3 2015 We found that carnosic acid markedly induced TRAIL-mediated apoptosis in human renal carcinoma (Caki, ACHN, and A498), and human hepatocellular carcinoma (SK-HEP-1), and human breast carcinoma (MDA-MB-231) cells, but not normal cells (TMCK-1 and HSF). salvin 14-27 TNF superfamily member 10 Homo sapiens 45-50 28440400-8 2017 The death receptor (DR) of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) was enhanced in carnosic acid and fisetin combined treatment. salvin 107-120 TNF superfamily member 10 Homo sapiens 84-89 28282784-8 2017 The elevation of decoy receptor 1 and 2 (DcR1 and DcR2) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) were enhanced for carnosic acid and tamoxifen cooperation. salvin 142-155 TNF superfamily member 10 Homo sapiens 60-115 28282784-8 2017 The elevation of decoy receptor 1 and 2 (DcR1 and DcR2) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) were enhanced for carnosic acid and tamoxifen cooperation. salvin 142-155 TNF superfamily member 10 Homo sapiens 117-122 25596735-7 2015 Taken together, our study demonstrates that carnosic acid enhances sensitization against TRAIL-mediated apoptosis through the down-regulation of c-FLIP and Bcl-2 expression, and up-regulation of ER stress-mediated DR5, Bim, and PUMA expression at the transcriptional levels. salvin 44-57 TNF superfamily member 10 Homo sapiens 89-94