PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35631123-5	2022	This finding prompted us to investigate the possibility of testing imipramine, an antidepressant drug known to inhibit NPC1 function by interfering with intracellular cholesterol trafficking.	Imipramine	67-77	NPC intracellular cholesterol transporter 1	Homo sapiens	119-123	
18711208-8	2008	U18666A and imipramine, agents that mimic cholesterol trafficking defects of Neimann-Pick type C disease, attenuate cholesterol efflux without altering ABCA1 expression; thus, intestinal NPC1 may facilitate cholesterol movement to ABCA1.	Imipramine	12-22	NPC intracellular cholesterol transporter 1	Homo sapiens	187-191	
31866985-3	2019	Both pretreatment of B. mori embryonic cells (BmE) with NPC1 antagonists (imipramine or U18666A) and down-regulation of NPC1 expression resulted in a significant reduction in baculovirus BmNPV (B. mori nuclear polyhedrosis virus) infectivity.	Imipramine	74-84	NPC intracellular cholesterol transporter 1	Homo sapiens	56-60