PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28760302-7 2017 In polycythemia vera, a novel interferon administered every 2 weeks is being developed for front-line therapy in high-risk individuals, and inhibitors of human double minute 2 (HDM2) have shown promise in preclinical studies, as have HDAC inhibitors such as givinostat (both in the laboratory and in the clinic). givinostat 258-268 MDM2 proto-oncogene Homo sapiens 177-181