PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31837525-2 2020 In addition to the structural characterization of vandetanib metabolites, individual rat enzymes [cytochrome P450 (CYP) and flavin-containing monooxygenase (FMO)] capable of oxidizing vandetanib were identified. vandetanib 184-194 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 98-113 31837525-2 2020 In addition to the structural characterization of vandetanib metabolites, individual rat enzymes [cytochrome P450 (CYP) and flavin-containing monooxygenase (FMO)] capable of oxidizing vandetanib were identified. vandetanib 184-194 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 115-118 31837525-6 2020 Results of the present study explain differences between the CYP- and FMO-catalyzed vandetanib oxidation in rat and human liver reported previously and the enzymatic mechanisms underlying this phenomenon. vandetanib 84-94 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 61-64