PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29449346-0	2018	Shikonin suppresses proliferation and induces apoptosis in endometrioid endometrial cancer cells via modulating miR-106b/PTEN/AKT/mTOR signaling pathway.	shikonin	0-8	phosphatase and tensin homolog	Homo sapiens	121-125	
33391404-0	2021	Shikonin inhibits migration and invasion of triple-negative breast cancer cells by suppressing epithelial-mesenchymal transition via miR-17-5p/PTEN/Akt pathway.	shikonin	0-8	phosphatase and tensin homolog	Homo sapiens	143-147	
33391404-17	2021	Conclusions: Shikonin inhibits migration and invasion of TNBC cells by suppressing EMT via miR-17-5p/PTEN/Akt pathway.	shikonin	13-21	phosphatase and tensin homolog	Homo sapiens	101-105	
29843123-10	2018	Moreover, shikonin increased the PTEN level and inactivated the PI3K/AKT signaling pathway, subsequently upregulating BAX in K562 cells.	shikonin	10-18	phosphatase and tensin homolog	Homo sapiens	33-37	
29843123-13	2018	CONCLUSION: These results demonstrated that shikonin inhibits CML proliferation and migration and induces apoptosis by the PTEN/PI3K/AKT pathway, revealing the effects of shikonin therapy on CML.	shikonin	44-52	phosphatase and tensin homolog	Homo sapiens	123-127	
29843123-13	2018	CONCLUSION: These results demonstrated that shikonin inhibits CML proliferation and migration and induces apoptosis by the PTEN/PI3K/AKT pathway, revealing the effects of shikonin therapy on CML.	shikonin	171-179	phosphatase and tensin homolog	Homo sapiens	123-127