PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28941798-6	2017	The aim of this study was to investigate the potential inhibition of shikonin against CYP1A2, CYP2B1/6, CYP2C9/11, CYP2D1/6, CYP2E1 and CYP3A2/4 activities in human and rat liver microsomes through cocktail approach in vitro.	shikonin	69-77	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	104-110	
28941798-8	2017	In human liver microsomes, shikonin was not only a mixed inhibitor of CYP1A2, CYP2B6, CYP2C9, CYP2D6 and CYP3A4, but also a competitive inhibitor of CYP2E1, with Ki values no more than 7.72muM.	shikonin	27-35	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	86-92