PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32824616-3 2020 The Smac-mimetic birinapant is a substrate of the multidrug resistance protein 1 (MDR1) efflux pump, and therefore inhibitors of MDR1 increase intracellular concentration of birinapant in MDR1 expressing cells. birinapant 17-27 ATP binding cassette subfamily B member 1 Homo sapiens 50-80 32824616-3 2020 The Smac-mimetic birinapant is a substrate of the multidrug resistance protein 1 (MDR1) efflux pump, and therefore inhibitors of MDR1 increase intracellular concentration of birinapant in MDR1 expressing cells. birinapant 17-27 ATP binding cassette subfamily B member 1 Homo sapiens 82-86 32824616-3 2020 The Smac-mimetic birinapant is a substrate of the multidrug resistance protein 1 (MDR1) efflux pump, and therefore inhibitors of MDR1 increase intracellular concentration of birinapant in MDR1 expressing cells. birinapant 17-27 ATP binding cassette subfamily B member 1 Homo sapiens 129-133 32824616-3 2020 The Smac-mimetic birinapant is a substrate of the multidrug resistance protein 1 (MDR1) efflux pump, and therefore inhibitors of MDR1 increase intracellular concentration of birinapant in MDR1 expressing cells. birinapant 17-27 ATP binding cassette subfamily B member 1 Homo sapiens 129-133 32824616-3 2020 The Smac-mimetic birinapant is a substrate of the multidrug resistance protein 1 (MDR1) efflux pump, and therefore inhibitors of MDR1 increase intracellular concentration of birinapant in MDR1 expressing cells. birinapant 174-184 ATP binding cassette subfamily B member 1 Homo sapiens 50-80 32824616-3 2020 The Smac-mimetic birinapant is a substrate of the multidrug resistance protein 1 (MDR1) efflux pump, and therefore inhibitors of MDR1 increase intracellular concentration of birinapant in MDR1 expressing cells. birinapant 174-184 ATP binding cassette subfamily B member 1 Homo sapiens 82-86 32824616-3 2020 The Smac-mimetic birinapant is a substrate of the multidrug resistance protein 1 (MDR1) efflux pump, and therefore inhibitors of MDR1 increase intracellular concentration of birinapant in MDR1 expressing cells. birinapant 174-184 ATP binding cassette subfamily B member 1 Homo sapiens 129-133 32824616-3 2020 The Smac-mimetic birinapant is a substrate of the multidrug resistance protein 1 (MDR1) efflux pump, and therefore inhibitors of MDR1 increase intracellular concentration of birinapant in MDR1 expressing cells. birinapant 174-184 ATP binding cassette subfamily B member 1 Homo sapiens 129-133 32824616-5 2020 In this study, we investigated whether combining the clinical drugs, birinapant and the MDR1 inhibitor zosuquidar, increases the efficacy of birinapant in killing HBV expressing liver cells. birinapant 141-151 ATP binding cassette subfamily B member 1 Homo sapiens 88-92