PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34714906-5	2021	In addition, Birinapant could inhibit tumor growth via increasing the secretion of and the sensitivity to TNF-alpha in a TNBC xenotransplantation mouse model.	birinapant	13-23	tumor necrosis factor	Mus musculus	106-115	
28286228-6	2017	IL-1 and TNF-alpha levels in the serum were markedly decreased in birinapant pretreatment mice compared with control mice (P<0.05).The cellular inhibitor of apoptosis protein 1 (cIAP1) expression in liver resident macrophage (Kupffer cells, KCs) was significantly decreased in the Birinapant group compared to the Vehicle group (P<0.05).	birinapant	66-76	tumor necrosis factor	Mus musculus	9-18	
25431358-10	2015	Docetaxel showed synergism with birinapant +- TNFalpha in vitro.	birinapant	32-42	tumor necrosis factor	Mus musculus	46-54	
33257690-9	2020	In CMS2 cell lines, Birinapant exhibited synergistic effects in combination with TNFalpha, suggesting that Birinapant can restore extrinsic apoptosis signaling in the context of inflammatory signals in this subtype.	birinapant	107-117	tumor necrosis factor	Mus musculus	81-89	
33257690-11	2020	We observed increased cell death during Birinapant single treatment in these co-cultures, which was abrogated by anti-TNFalpha-neutralizing antibodies.	birinapant	40-50	tumor necrosis factor	Mus musculus	118-126