PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28286228-0 2017 The SMAC mimetic birinapant attenuates lipopolysaccharide-induced liver injury by inhibiting the tumor necrosis factor receptor-associated factor 3 degradation in Kupffer cells. birinapant 17-27 diablo, IAP-binding mitochondrial protein Mus musculus 4-8 33080008-1 2020 The specific targeting of inhibitor of apoptosis (IAP) proteins by Smac-mimetic (SM) drugs, such as birinapant, has been tested in clinical trials of acute myeloid leukemia (AML) and certain solid cancers. birinapant 100-110 diablo, IAP-binding mitochondrial protein Mus musculus 67-71 31032587-0 2018 [Anti-hepatoma effects of Smac analogue Birinapant and its related molecular mechanism]. birinapant 40-50 diablo, IAP-binding mitochondrial protein Mus musculus 26-30 27194728-3 2016 Potent ex vivo activity of the SMAC mimetic (SM) birinapant correlated with marked in vivo antileukemic effects, as indicated by delayed engraftment, decreased leukemia burden, and prolonged survival of xenografted mice. birinapant 49-59 diablo, IAP-binding mitochondrial protein Mus musculus 31-35 25431358-3 2015 We investigated the effects of birinapant, a novel, second mitochondria-derived activator of caspases (SMAC)-mimetic that targets inhibitor of apoptosis proteins, alone and in combination with TNFalpha, TRAIL, or chemotherapy docetaxel. birinapant 31-41 diablo, IAP-binding mitochondrial protein Mus musculus 103-107