PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30845975-8 2019 In contrast, the bortezomib/birinapant regimen upregulated TRAF3, downregulated TRAF2, and diminished p52 processing and BCL-XL expression, consistent with disruption of the non-canonical NF-kappaB pathway. birinapant 28-38 TNF receptor associated factor 2 Homo sapiens 80-85 30845975-9 2019 TRAF3 knockdown, ectopic TRAF2, or BCL-XL expression significantly diminished birinapant/bortezomib toxicity. birinapant 78-88 TNF receptor associated factor 2 Homo sapiens 25-30 24563541-0 2014 Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-kappaB activation, and is active in patient-derived xenograft models. birinapant 0-10 TNF receptor associated factor 2 Homo sapiens 55-60 24563541-0 2014 Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-kappaB activation, and is active in patient-derived xenograft models. birinapant 12-19 TNF receptor associated factor 2 Homo sapiens 55-60 24563541-8 2014 Birinapant preferentially targeted the TRAF2-associated cIAP1 and cIAP2 with subsequent inhibition of TNF-induced NF-kappaB activation. birinapant 0-10 TNF receptor associated factor 2 Homo sapiens 39-44