PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7043175-2 1982 Compared to placebo conditions, clopamide monotherapy significantly increased serum low-density lipoprotein cholesterol (LDL-C) by 13% (p less than 0.025). Clopamide 32-41 component of oligomeric golgi complex 2 Homo sapiens 84-119 6137325-6 1983 Increases in LDL-C caused by chlorthalidone monotherapy were prevented or reversed by the addition of a beta-blocker, usually propranolol or atenolol (n = 18); increases in LDL-C during clopamide monotherapy were reversed after the addition of the beta-blocker pindolol (10 mg/day, n = 17). Clopamide 186-195 component of oligomeric golgi complex 2 Homo sapiens 173-178 7043175-2 1982 Compared to placebo conditions, clopamide monotherapy significantly increased serum low-density lipoprotein cholesterol (LDL-C) by 13% (p less than 0.025). Clopamide 32-41 component of oligomeric golgi complex 2 Homo sapiens 121-126 7043175-6 1982 These findings suggest that antihypertensive combination treatment with low doses of clopamide and pindolol is not only effective and well tolerated, but may also avoid the increase in serum LDL-C levels occurring when the thiazide-like diuretic is given alone. Clopamide 85-94 component of oligomeric golgi complex 2 Homo sapiens 191-196