PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27161375-5 2016 These results indicate that GA is effective in suppressing PRL hyperactivity caused by the blockade of dopamine D2 receptors. 18alpha-glycyrrhetinic acid 28-30 prolactin Rattus norvegicus 59-62 27161375-1 2016 The purpose of this study was to examine the effects of 18beta-glycyrrhetinic acid (GA), a novel naturally derived agent, in suppressing prolactin (PRL) hyperactivity and reducing antipsychotic-induced hyperprolactinemia (hyperPRL) and the underlying mechanisms in in vitro and in vivo models. 18alpha-glycyrrhetinic acid 56-82 prolactin Rattus norvegicus 148-151 27161375-1 2016 The purpose of this study was to examine the effects of 18beta-glycyrrhetinic acid (GA), a novel naturally derived agent, in suppressing prolactin (PRL) hyperactivity and reducing antipsychotic-induced hyperprolactinemia (hyperPRL) and the underlying mechanisms in in vitro and in vivo models. 18alpha-glycyrrhetinic acid 84-86 prolactin Rattus norvegicus 148-151 27161375-2 2016 GA treatment for 24 h inhibited PRL synthesis and secretion in MMQ cells and cultured pituitary cells in a dose-dependent fashion; but this effect was not reproduced in GH3 cells that lack the expression of functional dopamine D2 receptors. 18alpha-glycyrrhetinic acid 0-2 prolactin Rattus norvegicus 32-35