PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11904152-5	2002	Since iNOS transcription has been shown to be under the control of the transcription factor nuclear factor kappaB (NF-kappaB), the effects of GA on NF-kappaB activation were examined.	18alpha-glycyrrhetinic acid	142-144	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	148-157	
11904152-6	2002	Transient expression assays with NF-kappaB binding sites linked to the luciferase gene revealed that the increased level of iNOS mRNA, induced by GA, was mediated by the NF-kappaB transcription factor complex.	18alpha-glycyrrhetinic acid	146-148	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	33-42	
11904152-6	2002	Transient expression assays with NF-kappaB binding sites linked to the luciferase gene revealed that the increased level of iNOS mRNA, induced by GA, was mediated by the NF-kappaB transcription factor complex.	18alpha-glycyrrhetinic acid	146-148	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	170-179	
11904152-7	2002	By using DNA fragments containing the NF-kappaB binding sequence, GA was shown to activate the protein/DNA binding of NF-kappaB to its cognate site, as measured by electrophoretic mobility shift assay.	18alpha-glycyrrhetinic acid	66-68	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	38-47	
11904152-7	2002	By using DNA fragments containing the NF-kappaB binding sequence, GA was shown to activate the protein/DNA binding of NF-kappaB to its cognate site, as measured by electrophoretic mobility shift assay.	18alpha-glycyrrhetinic acid	66-68	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	118-127	
11904152-8	2002	These results demonstrate that GA stimulates NO production and is able to up-regulate iNOS expression through NF-kappaB transactivation in macrophages.	18alpha-glycyrrhetinic acid	31-33	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	110-119	
21644799-0	2011	Glycyrrhizic acid and 18beta-glycyrrhetinic acid modulate lipopolysaccharide-induced inflammatory response by suppression of NF-kappaB through PI3K p110delta and p110gamma inhibitions.	18alpha-glycyrrhetinic acid	22-48	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	125-134	
29973878-0	2018	18beta-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK-TRAF6 Interactions and NF-kappaB and MAPK Signaling Pathways.	18alpha-glycyrrhetinic acid	0-26	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	131-140	
29973878-6	2018	For underlying molecular mechanisms, 18beta-GA inhibited RANKL-induced phosphorylation of p65, p50, and IkappaB, blocked p65 nuclear translocation and decreased the DNA-binding activity of NF-kappaB.	18alpha-glycyrrhetinic acid	37-46	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	95-98	
29973878-6	2018	For underlying molecular mechanisms, 18beta-GA inhibited RANKL-induced phosphorylation of p65, p50, and IkappaB, blocked p65 nuclear translocation and decreased the DNA-binding activity of NF-kappaB.	18alpha-glycyrrhetinic acid	37-46	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	189-198	
29973878-10	2018	Overall, our results demonstrated that 18beta-GA inhibited RANKL-induced osteoclastogenesis by inhibiting RANK expression in preosteoclasts and blocking the binding of RANK and TRAF6 which lead to the inhibition of NF-kappaB and MAPK signaling pathways.	18alpha-glycyrrhetinic acid	39-48	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	215-224	
16002718-0	2005	18 Beta-glycyrrhetinic acid triggers curative Th1 response and nitric oxide up-regulation in experimental visceral leishmaniasis associated with the activation of NF-kappa B.	18alpha-glycyrrhetinic acid	3-27	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	163-173