PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31615045-3	2019	Despite many reported health benefits, 3MGA and GA inhibit the 11-beta-hydrogenase type II enzyme (11beta-HSD2) oxidizing cortisol to cortisone.	18alpha-glycyrrhetinic acid	41-43	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	66-110	
28797028-12	2017	Pharmacological manipulation of 11beta-HSD2 activity by 18beta-glycyrrhetinic acid (GA) and silencing by specific siRNAs modulated the bioavailability of cortisol.	18alpha-glycyrrhetinic acid	56-82	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	32-43	
28797028-12	2017	Pharmacological manipulation of 11beta-HSD2 activity by 18beta-glycyrrhetinic acid (GA) and silencing by specific siRNAs modulated the bioavailability of cortisol.	18alpha-glycyrrhetinic acid	84-86	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	32-43	
23826195-6	2013	Inhibition of 11beta-HSD2 by 11beta-HSD inhibitor 18beta-glycyrrhetinic acid or 11beta-HSD2 shRNA significantly increased cortisol-induced apoptosis in Jurkat cells.	18alpha-glycyrrhetinic acid	50-76	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	14-25	
22067259-8	2012	Blocking of endogenous cortisol catabolism in keratinocytes with the 11beta-HSD2 inhibitor 18beta-glycyrrhetinic acid mimicked the effect of exogenous administration of hydrocortisone and partially prevented the detrimental effects induced by pemphigus vulgaris sera.	18alpha-glycyrrhetinic acid	91-117	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	69-80	
19429429-5	2009	18beta-glycyrrhetinic acid (GA), a metabolite of the natural product glycyrrhizin, is not selective and inhibits both 11beta-HSD1 and 11beta-HSD2.	18alpha-glycyrrhetinic acid	0-26	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	134-145	
19429429-5	2009	18beta-glycyrrhetinic acid (GA), a metabolite of the natural product glycyrrhizin, is not selective and inhibits both 11beta-HSD1 and 11beta-HSD2.	18alpha-glycyrrhetinic acid	28-30	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	134-145