PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11469860-1	2001	The azole-based P450 inhibitor ketoconazole is used to treat fungal infections and functions by blocking ergosterol biosynthesis in yeast.	Ergosterol	105-115	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	16-20	
2091733-2	1990	Currently, representatives of two classes of EBI antifungals are available: the squalene epoxidase inhibitors and those that interfere with cytochrome P450-dependent ergosterol synthesis.	Ergosterol	166-176	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	151-155	
2091733-8	1990	All the azole antifungals inhibit the cytochrome P450-dependent, 14 alpha-demethylase, a key enzyme in the synthesis of ergosterol, the main sterol in most fungal cells.	Ergosterol	120-130	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	49-53	
17954932-2	2007	In particular, the P450 protein Erg11/Cyp51 catalyzes a critical step in ergosterol synthesis, and the azole class of antifungal drugs inhibits Erg11.	Ergosterol	73-83	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	19-23