PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21453743-7	2011	delta-Tocotrienol also decreased cyclin D1, c-jun and MMP-7 protein levels in SW620 cells.	tocotrienol, delta	0-17	cyclin D1	Homo sapiens	33-42	
19035289-0	2008	Growth inhibition of human MDA-mB-231 breast cancer cells by delta-tocotrienol is associated with loss of cyclin D1/CDK4 expression and accompanying changes in the state of phosphorylation of the retinoblastoma tumor suppressor gene product.	tocotrienol, delta	61-78	cyclin D1	Homo sapiens	106-115	
19035289-5	2008	The site-specific inhibition of the phosphorylation of Rb by delta-tocotrienol was tightly associated with a marked reduction in the expression of cyclin D1 and its regulatory partner cyclin-dependant kinase 4 (CDK4), which is responsible for the phosphorylation of Rb at Ser780, Ser795, Ser 807/811 and Thr826.	tocotrienol, delta	61-78	cyclin D1	Homo sapiens	147-156	
19035289-8	2008	To the best of our knowledge, this study was the first to reveal that the target of cell proliferative inhibitory action of delta-tocotrienol in a model estrogen receptor-negative human breast cancer cell line MDA-MB-231 is mediated by the loss of cyclin D1 and associated suppression of site-specific Rb phosphorylation, suggesting its future development and use as an anticancer agent.	tocotrienol, delta	124-141	cyclin D1	Homo sapiens	248-257	
34056642-8	2021	The results suggest that delta-tocotrienol induces cell cycle arrest in CNE1 cells via the p16/CDK4/cyclin D1 signaling pathway.	tocotrienol, delta	25-42	cyclin D1	Homo sapiens	100-109