PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20823559-5 2010 Tyrosinase activity, amounts of tyrosinase and TRP-1 decreased dependent on dose : by 50 (25 microM delta-tocotrienol) to 75% (50 microM), 20 to 45% and 42 to 82% at 48 h, and by 25 to 50%, 75 to 80% and 78 to 77% at 72 h, respectively. tocotrienol, delta 100-117 tyrosinase Mus musculus 0-10 20823559-7 2010 From these findings, delta-tocotrienol at up to 50 microM dose-dependently caused a reduction in melanin content by the decrease of TRP-1 and TRP-2 as well as tyrosinase, and no cytotoxicity. tocotrienol, delta 21-38 tyrosinase Mus musculus 159-169