PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31177586-8	2019	Obeticholic acid inhibited hepatic TLR4 expression and increased hepatic matrix metalloproteinase-2 expression.	obeticholic acid	0-16	matrix metallopeptidase 2	Rattus norvegicus	73-99	
15860571-2	2005	In the present study, we investigated whether 6-ethyl chenodeoxycholic acid (6-ECDCA or INT-747), a semisynthetic derivative of chenodeoxycholic acid (CDCA), modulates tissue metalloproteinase inhibitor (TIMP)-1 and matrix metalloprotease (MMP)-2 expression/activity in HSCs and in the liver of rats rendered cirrhotic by 4-week administration of CCl(4).	obeticholic acid	46-75	matrix metallopeptidase 2	Rattus norvegicus	216-246	
35631351-7	2022	Although not significantly, MMP-2 activity decreased in the cortex of OCA-treated I/R rats.	obeticholic acid	70-73	matrix metallopeptidase 2	Rattus norvegicus	28-33	
32911524-1	2020	BACKGROUND: We have previously shown that obeticholic acid (OCA) upregulates the biliary excretion of asymmetric dimethylarginine (ADMA), an inhibitor of iNOS regulating the activity of matrix metalloproteinases (MMPs).	obeticholic acid	42-58	matrix metallopeptidase 2	Rattus norvegicus	213-217	
32911524-1	2020	BACKGROUND: We have previously shown that obeticholic acid (OCA) upregulates the biliary excretion of asymmetric dimethylarginine (ADMA), an inhibitor of iNOS regulating the activity of matrix metalloproteinases (MMPs).	obeticholic acid	60-63	matrix metallopeptidase 2	Rattus norvegicus	213-217