PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35597989-0	2022	Roxadustat promotes osteoblast differentiation and prevents estrogen deficiency-induced bone loss by stabilizing HIF-1alpha and activating the Wnt/beta-catenin signaling pathway.	roxadustat	0-10	catenin beta 1	Rattus norvegicus	147-159	
35597989-15	2022	Roxadustat activated the HIF-1alpha and Wnt/beta-catenin pathways.	roxadustat	0-10	catenin beta 1	Rattus norvegicus	44-56	
35597989-16	2022	HIF-1alpha knockdown or Wnt/beta-catenin pathway inhibition significantly attenuated roxadustat-promoted osteoblast differentiation.	roxadustat	85-95	catenin beta 1	Rattus norvegicus	28-40	
35597989-18	2022	Roxadustat upregulated the protein expression levels of the osteogenic markers, HIF-1alpha and beta-catenin in the bone tissue of OVX rats.	roxadustat	0-10	catenin beta 1	Rattus norvegicus	95-107