PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19235590-1 2009 We hypothesized that co-targeting the epidermal growth factor receptor (EGFR) and Src with the EGFR inhibitor gefitinib and the Src inhibitor AZD0530 would increase growth inhibition and impede migration. saracatinib 142-149 epidermal growth factor receptor Homo sapiens 38-70 19451593-8 2009 Combined anastrozole/AZD0530 reduced drug resistance and showed greater antitumor efficacy in vivo with greater Src and epidermal growth factor receptor inhibition and a greater increase in p27 and reduction of Ki-67 than either drug alone, supporting further evaluation of these putative predictors of response to combined Src/aromatase inhibition in vivo. saracatinib 21-28 epidermal growth factor receptor Homo sapiens 120-152 19235590-1 2009 We hypothesized that co-targeting the epidermal growth factor receptor (EGFR) and Src with the EGFR inhibitor gefitinib and the Src inhibitor AZD0530 would increase growth inhibition and impede migration. saracatinib 142-149 epidermal growth factor receptor Homo sapiens 72-76 34158343-6 2021 Additionally, AZD0530 was shown to inhibit the radiation-induced EGFR/PI3K/AKT pathway which in known to promote and regulate radioresistance and survival of GBM cells by radiation. saracatinib 14-21 epidermal growth factor receptor Homo sapiens 65-69 17918184-7 2008 Treatment with the dual specific Abl/c-Src kinase inhibitor AZD0530 significantly reduces the growth inhibitory effect of high EGF concentrations, signifying that EGFR induced IRF-1 is responsible for the observed growth inhibition. saracatinib 60-67 epidermal growth factor receptor Homo sapiens 163-167 23144237-9 2013 Saracatinib enhanced the effects of lapatinib, an EGFR/HER2 dual inhibitor, in SNU216 and NCI-N87 cells. saracatinib 0-11 epidermal growth factor receptor Homo sapiens 50-54