PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32616542-11	2020	SIGNIFICANCE STATEMENT: Weak CYP3A inhibition and/or induction can sometimes predict DDIs in the intestine but not the liver.	Didanosine	85-89	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	29-34	
35486324-2	2022	Ritonavir is a strong inhibitor for CYP3A4/5-mediated DDIs and has been proposed as a suitable alternative to ketoconazole.	Didanosine	54-58	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	36-44	
33276942-8	2020	Consequently, in the presence of potential DDIs through CYP3A4, and/or P-gp, LMWHs remain the first-line anticoagulant of choice for the long-term treatment of CAT.	Didanosine	43-47	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	56-62	
33830459-6	2021	Cabotegravir is mainly metabolized by UGT1A1, and rilpivirine is mainly metabolized by CYP3A4, therefore these agents are susceptible to DDIs with inhibitors, and particularly inducers of drug-metabolizing enzymes.	Didanosine	137-141	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	87-93	
30993551-2	2019	The current report investigates another important antiplatelet inhibitor, prasugrel, that is also activated through metabolism by CYP2B6, CYP2C19 and CYP3A4/5, for its CYP-based DDI potential with vonoprazan.	Didanosine	178-181	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	150-158	
34791318-3	2022	As many ARVs are substrates and/or inhibitors or inducers of CYP3A4, there is concern about DDIs with dexamethasone either as a perpetrator or a victim.	Didanosine	92-96	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	61-67