PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8045675-6 1994 We report here the results of studies designed to evaluate the effect of interleukin-3 (IL-3) on its ability to influence the hematopoietic toxicity associated with zidovudine and ddI following combination with retroviral-infected murine bone marrow cells. Didanosine 180-183 interleukin 3 Mus musculus 73-86 8045675-6 1994 We report here the results of studies designed to evaluate the effect of interleukin-3 (IL-3) on its ability to influence the hematopoietic toxicity associated with zidovudine and ddI following combination with retroviral-infected murine bone marrow cells. Didanosine 180-183 interleukin 3 Mus musculus 88-92 8045675-8 1994 Dose-escalation IL-3 provided protection of anti-viral drug induced suppression of progenitor cells when combined in the presence of the ID50 concentration of either zidovudine or ddI; however, when zidovudine and ddI were combined, IL-3 was less effective in providing protection against drug-induced toxicity at any concentration examined. Didanosine 180-183 interleukin 3 Mus musculus 16-20 8045675-8 1994 Dose-escalation IL-3 provided protection of anti-viral drug induced suppression of progenitor cells when combined in the presence of the ID50 concentration of either zidovudine or ddI; however, when zidovudine and ddI were combined, IL-3 was less effective in providing protection against drug-induced toxicity at any concentration examined. Didanosine 214-217 interleukin 3 Mus musculus 16-20