PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30637473-0 2019 STAT3 inhibition specifically in human monocytes and macrophages by CD163-targeted corosolic acid-containing liposomes. corosolic acid 83-97 CD163 molecule Homo sapiens 68-73 30637473-5 2019 Here, we report the first data on a CD163-targeted STAT3-inhibitory drug consisting of corosolic acid (CA) packaged within long-circulating liposomes (LCLs), which are CD163-targeted by modification with monoclonal anti-CD163 antibodies (alphaCD163)-CA-LCL-alphaCD163. corosolic acid 87-101 CD163 molecule Homo sapiens 36-41 30637473-5 2019 Here, we report the first data on a CD163-targeted STAT3-inhibitory drug consisting of corosolic acid (CA) packaged within long-circulating liposomes (LCLs), which are CD163-targeted by modification with monoclonal anti-CD163 antibodies (alphaCD163)-CA-LCL-alphaCD163. corosolic acid 87-101 CD163 molecule Homo sapiens 168-173 30637473-5 2019 Here, we report the first data on a CD163-targeted STAT3-inhibitory drug consisting of corosolic acid (CA) packaged within long-circulating liposomes (LCLs), which are CD163-targeted by modification with monoclonal anti-CD163 antibodies (alphaCD163)-CA-LCL-alphaCD163. corosolic acid 87-101 CD163 molecule Homo sapiens 168-173 21073634-3 2011 Among 130 purified natural compounds examined, corosolic acid significantly inhibited the expression of CD163, one of the phenotype markers of M2 macrophages, and also suppressed the secretion of IL-10, one of the anti-inflammatory cytokines preferentially produced by M2 macrophages, thus suggesting that corosolic acid suppresses M2 polarization of macrophages. corosolic acid 47-61 CD163 molecule Homo sapiens 104-109