PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24260055-0 2013 Corosolic acid enhances the antitumor effects of chemotherapy on epithelial ovarian cancer by inhibiting signal transducer and activator of transcription 3 signaling. corosolic acid 0-14 signal transducer and activator of transcription 3 Homo sapiens 105-155 30637473-0 2019 STAT3 inhibition specifically in human monocytes and macrophages by CD163-targeted corosolic acid-containing liposomes. corosolic acid 83-97 signal transducer and activator of transcription 3 Homo sapiens 0-5 30637473-5 2019 Here, we report the first data on a CD163-targeted STAT3-inhibitory drug consisting of corosolic acid (CA) packaged within long-circulating liposomes (LCLs), which are CD163-targeted by modification with monoclonal anti-CD163 antibodies (alphaCD163)-CA-LCL-alphaCD163. corosolic acid 87-101 signal transducer and activator of transcription 3 Homo sapiens 51-56 24738052-7 2014 Among 200 purified natural compounds examined, corosolic acid (CA) and oleanolic acid (OA), both are categorized in triterpenoid compounds, inhibited macrophage polarization to M2 phenotype by suppressing STAT3 activation. corosolic acid 47-61 signal transducer and activator of transcription 3 Homo sapiens 205-210 24260055-3 2013 The present study investigated whether corosolic acid (CA), which has been previously reported to be a STAT3 inhibitor, was able to increase the sensitivity to chemotherapeutic drugs in epithelial ovarian cancer cells. corosolic acid 39-53 signal transducer and activator of transcription 3 Homo sapiens 103-108 21073634-0 2011 Corosolic acid inhibits glioblastoma cell proliferation by suppressing the activation of signal transducer and activator of transcription-3 and nuclear factor-kappa B in tumor cells and tumor-associated macrophages. corosolic acid 0-14 signal transducer and activator of transcription 3 Homo sapiens 89-139 21073634-4 2011 Furthermore, corosolic acid inhibited the proliferation of glioblastoma cells, U373 and T98G, and the activation of signal transducer and activator of transcription-3 (STAT3) and nuclear factor-kappa B (NF-kappaB) in both human macrophages and glioblastoma cells. corosolic acid 13-27 signal transducer and activator of transcription 3 Homo sapiens 116-166 21073634-4 2011 Furthermore, corosolic acid inhibited the proliferation of glioblastoma cells, U373 and T98G, and the activation of signal transducer and activator of transcription-3 (STAT3) and nuclear factor-kappa B (NF-kappaB) in both human macrophages and glioblastoma cells. corosolic acid 13-27 signal transducer and activator of transcription 3 Homo sapiens 168-173 21073634-5 2011 These results indicate that corosolic acid suppresses the M2 polarization of macrophages and tumor cell proliferation by inhibiting both STAT3 and NF-kappaB activation. corosolic acid 28-42 signal transducer and activator of transcription 3 Homo sapiens 137-142