PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35046793-11	2021	Under low-glucose and hypoxic conditions, CGS21680 treatment promoted macrophage M2 polarization, increased the expression of PPARgamma, P65, and interleukin-10 (IL-10) and suppressed the expression of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta).	2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine	42-50	tumor necrosis factor	Mus musculus	202-229	
35046793-11	2021	Under low-glucose and hypoxic conditions, CGS21680 treatment promoted macrophage M2 polarization, increased the expression of PPARgamma, P65, and interleukin-10 (IL-10) and suppressed the expression of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta).	2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine	42-50	tumor necrosis factor	Mus musculus	231-240	
35046793-13	2021	The downregulation of TNF-alpha and IL-1beta by CGS21680 was less affected by PPARgamma knockdown.	2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine	48-56	tumor necrosis factor	Mus musculus	22-31	
21593451-8	2011	In Teff, A2aR activation (CGS21680) potently inhibited the release of IL-1, IL-2, IL-3, IL-4, IL-12, IL-13, IFN-gamma, TNF-alpha, granulocyte-macrophage colony-stimulating factor (GM-CSF), CCL3, and CCL4.	2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine	26-34	tumor necrosis factor	Mus musculus	119-128	
17321471-5	2007	The non-selective adenosine receptor agonist NECA, and the selective A(2A) receptor agonist CGS21680 also inhibited TNF-alpha production even more potently (IC(50)=4.8 and 2.3 nM, respectively).	2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine	92-100	tumor necrosis factor	Mus musculus	116-125