PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25762024-4 2015 However, an extension in CGS21680 compared with adenosine, the (2-carboxyethyl)phenylethylamino group, binds in an extended vestibule formed from transmembrane regions 2 and 7 (TM2 and TM7) and extracellular loops 2 and 3 (EL2 and EL3). 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine 25-33 spectrin alpha, erythrocytic 1 Homo sapiens 223-226 23500543-5 2013 The loop exchange entailed significant effects: The A2A-selective agonist CGS21680, while being completely inactive at A2BARs, showed high affinity for the mutant A2B(EL2-A2A)AR, and was able to fully activate the receptor. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine 74-82 spectrin alpha, erythrocytic 1 Homo sapiens 167-170