PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21430794-0 2011 Increase in IL-6 levels among major depressive disorder patients after a 6-week treatment with duloxetine 60 mg/day: a preliminary observation. Duloxetine Hydrochloride 95-105 interleukin 6 Homo sapiens 12-16 26556688-4 2015 RESULTS: IL-6 variants rs2066992 and rs10242595 were nominally associated with response to duloxetine (p = 0.047 and p = 0.028, respectively). Duloxetine Hydrochloride 91-101 interleukin 6 Homo sapiens 9-13 26556688-7 2015 CONCLUSION: Our findings tentatively suggest that IL-6 variants play a role in duloxetine and placebo response, which warrants further investigation. Duloxetine Hydrochloride 79-89 interleukin 6 Homo sapiens 50-54 21430794-9 2011 Nonetheless, the trend of increasing IL-6 levels observed in responder patients treated with duloxetine should prompt further controlled, extended studies with larger samples, with the specific aim of better assessing a putative differential role of norepinephrinergic antidepressant stimulation of serotonergic reuptake inhibition in determining modifications in IL-6 levels. Duloxetine Hydrochloride 93-103 interleukin 6 Homo sapiens 37-41 21430794-9 2011 Nonetheless, the trend of increasing IL-6 levels observed in responder patients treated with duloxetine should prompt further controlled, extended studies with larger samples, with the specific aim of better assessing a putative differential role of norepinephrinergic antidepressant stimulation of serotonergic reuptake inhibition in determining modifications in IL-6 levels. Duloxetine Hydrochloride 93-103 interleukin 6 Homo sapiens 364-368