PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27772765-0	2016	Pretreated duloxetine protects hippocampal CA1 pyramidal neurons from ischemia-reperfusion injury through decreases of glial activation and oxidative stress.	Duloxetine Hydrochloride	11-21	carbonic anhydrase 1	Homo sapiens	43-46	
27772765-2	2016	In the present study, we investigated the neuroprotective effect of pre-treated DXT in the hippocampal CA1 region following transient global cerebral ischemia.	Duloxetine Hydrochloride	80-83	carbonic anhydrase 1	Homo sapiens	103-106	
27772765-3	2016	Pre-treatment with 40mg/kg DXT protected pyramidal neurons in the CA1 region from ischemia-reperfusion injury.	Duloxetine Hydrochloride	27-30	carbonic anhydrase 1	Homo sapiens	66-69	
27772765-5	2016	On the other hand, we found that pre-treatment with DXT did not increase 4-hydroxy-2-noneal (a marker for lipid peroxidation) and significantly increased the expression of Cu, Zn-superoxide dismutase, an antioxidant, in the CA1 pyramidal neurons compared with non-treated those after ischemia-reperfusion.	Duloxetine Hydrochloride	52-55	carbonic anhydrase 1	Homo sapiens	224-227