PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30272260-0 2018 LY3009120, a pan-Raf kinase inhibitor, inhibits adipogenesis of 3T3-L1 cells by controlling the expression and phosphorylation of C/EBP-alpha, PPAR-gamma, STAT-3, FAS, ACC, perilipin A, and AMPK. LY3009120 0-9 signal transducer and activator of transcription 3 Mus musculus 155-161 30272260-9 2018 LY3009120 reduced not only the expression of CCAAT/enhancer-binding protein-alpha (C/EBP-alpha), peroxisome proliferator-activated receptor-gamma (PPAR-gamma), fatty acid synthase (FAS), acetyl CoA carboxylase (ACC), and perilipin A, but also reduced the phosphorylation of signal transducer and activator of transcription-3 (STAT-3) in differentiating 3T3-L1 cells. LY3009120 0-9 signal transducer and activator of transcription 3 Mus musculus 274-324 30272260-9 2018 LY3009120 reduced not only the expression of CCAAT/enhancer-binding protein-alpha (C/EBP-alpha), peroxisome proliferator-activated receptor-gamma (PPAR-gamma), fatty acid synthase (FAS), acetyl CoA carboxylase (ACC), and perilipin A, but also reduced the phosphorylation of signal transducer and activator of transcription-3 (STAT-3) in differentiating 3T3-L1 cells. LY3009120 0-9 signal transducer and activator of transcription 3 Mus musculus 326-332 30272260-11 2018 In summary, this is the first report, to the best of our knowledge, demonstrating that LY3009120 has an anti-adipogenic effect on 3T3-L1 cells, which may be mediated through control of the expression and phosphorylation of C/EBP-alpha, PPAR-gamma, STAT-3, FAS, ACC, perilipin A, and AMPK. LY3009120 87-96 signal transducer and activator of transcription 3 Mus musculus 248-254