PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17875398-7 2008 WRN-depleted HeLa cells treated with hydroquinone also displayed an increase in the amount of DNA double-strand breaks as determined by the Comet assay, and an elevated DNA damage response as indicated by the sevenfold induction of gammaH2AX and acetyl-p53 (Lys373 and Lys382) over control levels. gammah2ax 232-241 WRN RecQ like helicase Homo sapiens 0-3 16287861-4 2005 Withdrawal of WRN or BLM produced accelerated cellular senescence phenotype and DNA damage response in normal fibroblasts, as evidenced by induction of gammaH2AX and 53BP1 nuclear foci. gammah2ax 152-161 WRN RecQ like helicase Homo sapiens 14-17