PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24434636-5	2014	By using specific S1P receptor agonists (SEW2871, FTY720-P) and antagonist (JTE013) we identified an important role for S1P receptor 1 in the modulation of the cytokine profile.	JTE 013	76-82	sphingosine-1-phosphate receptor 1	Mus musculus	120-134	
21145832-13	2011	In contrast, JTE-013 (an S1P(2) antagonist) and silencing of S1P(2) expression enhanced S1P-induced migration.	JTE 013	13-20	sphingosine-1-phosphate receptor 1	Mus musculus	25-28	
24292566-10	2014	The inhibitory effect of S1P was abolished in the presence of the S1P2 receptor antagonist JTE-013 both in vitro and in vivo.	JTE 013	91-98	sphingosine-1-phosphate receptor 1	Mus musculus	25-28	
23307289-7	2013	However, JTE-013 (an S1P(2) antagonist) blocked the S1P-induced action.	JTE 013	9-16	sphingosine-1-phosphate receptor 1	Mus musculus	21-24	
23307289-7	2013	However, JTE-013 (an S1P(2) antagonist) blocked the S1P-induced action.	JTE 013	9-16	sphingosine-1-phosphate receptor 1	Mus musculus	52-55	
20060809-7	2010	Moreover, administration of JTE-013, a S1P(2)-specific antagonist, to WT mice ameliorated STZ-induced blood glucose elevation and reduced the incidence of diabetes.	JTE 013	28-35	sphingosine-1-phosphate receptor 1	Mus musculus	39-42	
20554039-4	2010	The S1P-mediated contraction was abolished by JTE-013, a selective S1P receptor 2 (S1PR2) antagonist, but not by W123, a selective S1PR1 antagonist, and BML-241, a selective S1PR3 antagonist.	JTE 013	46-53	sphingosine-1-phosphate receptor 1	Mus musculus	4-7	
21687504-5	2011	When analyzing S1P-induced vasoconstriction in mouse basilar artery, we observed that JTE-013 inhibited not only the effect of S1P, but also the effect of U46619, endothelin-1 or high KCl; JTE-013 strongly inhibited responses to S1P in S1P(2) receptor knockout mice.	JTE 013	86-93	sphingosine-1-phosphate receptor 1	Mus musculus	15-18	
21687504-5	2011	When analyzing S1P-induced vasoconstriction in mouse basilar artery, we observed that JTE-013 inhibited not only the effect of S1P, but also the effect of U46619, endothelin-1 or high KCl; JTE-013 strongly inhibited responses to S1P in S1P(2) receptor knockout mice.	JTE 013	86-93	sphingosine-1-phosphate receptor 1	Mus musculus	127-130	
21687504-5	2011	When analyzing S1P-induced vasoconstriction in mouse basilar artery, we observed that JTE-013 inhibited not only the effect of S1P, but also the effect of U46619, endothelin-1 or high KCl; JTE-013 strongly inhibited responses to S1P in S1P(2) receptor knockout mice.	JTE 013	86-93	sphingosine-1-phosphate receptor 1	Mus musculus	127-130	
21687504-5	2011	When analyzing S1P-induced vasoconstriction in mouse basilar artery, we observed that JTE-013 inhibited not only the effect of S1P, but also the effect of U46619, endothelin-1 or high KCl; JTE-013 strongly inhibited responses to S1P in S1P(2) receptor knockout mice.	JTE 013	86-93	sphingosine-1-phosphate receptor 1	Mus musculus	127-130	
18026125-6	2008	JTE-013 inhibited not only S1P-induced vasoconstriction, but also KCl-, U46619- and endothelin-1-induced constriction.	JTE 013	0-7	sphingosine-1-phosphate receptor 1	Mus musculus	27-30	
18026125-11	2008	The purported S1P(2) receptor antagonist JTE-013 does not appear to be selective, at least in rodents.	JTE 013	41-48	sphingosine-1-phosphate receptor 1	Mus musculus	14-17	
12810709-5	2003	In addition, JTE013 abrogated the inhibition by sphingosine, which is the S1P precursor but not an agonist for S1P receptors, indicating that the sphingosine effects were mediated via S1P2 stimulation, most likely by S1P that was converted from sphingosine.	JTE 013	13-19	sphingosine-1-phosphate receptor 1	Mus musculus	74-77