PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33835632-10	2021	Following GM treatment, the phosphorylation of the PI3K, AKT, and mTOR proteins was reduced in the liver of CCl4 -treated rats and TGF-beta1-stimulated LX-2 cells, indicating that GM may attenuate hepatic fibrosis via the PI3K/AKT/mTOR signalling pathway.	germacrone	10-12	mechanistic target of rapamycin kinase	Rattus norvegicus	66-70	
33835632-10	2021	Following GM treatment, the phosphorylation of the PI3K, AKT, and mTOR proteins was reduced in the liver of CCl4 -treated rats and TGF-beta1-stimulated LX-2 cells, indicating that GM may attenuate hepatic fibrosis via the PI3K/AKT/mTOR signalling pathway.	germacrone	180-182	mechanistic target of rapamycin kinase	Rattus norvegicus	66-70	
32145743-10	2020	More importantly, germacrone significantly inhibited the expression of PI3K III, LC3, and Beclin-1 in OGD/R-injured PC12 cells, and up-regulated the expressionof PI3K I, Akt, mTOR, and Bcl-2 proteins in cells, and this inhibited or up-regulated effect was reversed by PI3K I inhibitor (ZSTK474).	germacrone	18-28	mechanistic target of rapamycin kinase	Rattus norvegicus	175-179	
32145743-11	2020	CONCLUSION: The above results indicated that germacrone could inhibit the autophagy effect in OGD/R injury model of PC12 cells, the mechanism of inhibition was regulated by PI3K III/Beclin-1/Bcl-2 and PI3K I/Akt/mTOR pathways, thereby improving the cell viability of PC12 cells and playing a neuroprotective role, which provided a new drug for the treatment of OGD/R.	germacrone	45-55	mechanistic target of rapamycin kinase	Rattus norvegicus	212-216