PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27573551-0	2016	Germacrone Inhibits Estrogen Receptor alpha-Mediated Transcription in MCF-7 Breast Cancer Cells.	germacrone	0-10	estrogen receptor 1	Homo sapiens	20-43	
27573551-5	2016	Here, we demonstrated that germacrone inhibits ERalpha-mediated gene expression at the transcriptional level in MCF-7 cells.	germacrone	27-37	estrogen receptor 1	Homo sapiens	47-54	
27573551-6	2016	Germacrone inhibits the recruitment of ERalpha to the estrogen response element on chromatin and consequently compromises the binding of switch/sucrose non-fermentable chromatin remodeling complex and RNA polymerase II to target gene promoter, thereby inhibiting the estrogen-induced chromatin accessibility.	germacrone	0-10	estrogen receptor 1	Homo sapiens	39-46	
27573551-8	2016	Our results not only provide substantial molecular mechanism of germacrone on ERalpha-mediated signaling in breast cancer cells but also demonstrate the benefits of germacrone as a combination therapy with other drugs for the treatment of breast cancer.	germacrone	64-74	estrogen receptor 1	Homo sapiens	78-85