PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25854346-0	2015	Inhibitory effect of phenethyl isothiocyanate against benzo[a] pyrene-induced rise in CYP1A1 mRNA and apoprotein levels as its chemopreventive properties.	phenethyl isothiocyanate	21-45	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	86-92	
25854346-4	2015	OBJECTIVE: To evaluate the inhibitory effects of PEITC against benzo[a]pyrene-induced rise in rat liver CYP1A1 mRNA and apoprotein levels.	phenethyl isothiocyanate	49-54	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	104-110	
25854346-6	2015	RESULTS: Findings revealed that PEITC inhibited benzo[a]pyrene-induced rise in rat liver CYP1A1 mRNA in a dose-dependent manner as well as the apoprotein levels of CYP1A.	phenethyl isothiocyanate	32-37	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	89-95	
11346483-5	2001	Significantly lower concentrations of curcumin(s) than isothiocyanates achieved 50% inhibition of activity of CYP 1A1 and 1A2, while concentrations of C (4 microM), bdmC (2.5 microM) required to inhibit CYP 2B1 were slightly higher than that of PEITC (1.3 microM), suggesting curcumin(s) to be effective inhibitors of CYP 2B1 as well.	phenethyl isothiocyanate	245-250	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	110-117	
11346483-7	2001	These results suggest that turmeric/curcumin(s) as in the case of isothiocyanate, PEITC, are likely to inhibit activation of carcinogens metabolized by CYP450 isozymes, namely, CYP 1A1, 1A2 and 2B1.	phenethyl isothiocyanate	82-87	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	177-184	
22174033-4	2012	Moreover, PEITC suppressed in concentration-dependent manner the benzo[a]pyrene-mediated rise in rat hepatic CYP1A1 mRNA levels in rat slices.	phenethyl isothiocyanate	10-15	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	109-115