PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8625495-0 1996 Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate. phenethyl isothiocyanate 118-142 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 76-95 15224350-7 2004 Both IM and NS-398 inhibited adduct formation by HCA to nearly the same extent, indicating involvement of COX-2 rather than COX-1, while CYP1A2 activity in HCA-7 cells was demonstrated by addition of PEITC. phenethyl isothiocyanate 200-205 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 137-143 11454729-2 2001 PEITC competitively inhibited phenacetin O-deethylase activity catalyzed by CYP1A2 (K(i) = 4.5 +/- 1.0 microM) and coumarin 7-hydroxylase activity catalyzed by CYP2A6 (K(i) = 18.2 +/- 2.5 microM). phenethyl isothiocyanate 0-5 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 76-82