PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27306439-0 2016 Fluorofenidone attenuates pulmonary inflammation and fibrosis via inhibiting the activation of NALP3 inflammasome and IL-1beta/IL-1R1/MyD88/NF-kappaB pathway. 5-methyl-1-(3-fluorophenyl)-2-(1H)-pyridone 0-14 myeloid differentiation primary response gene 88 Mus musculus 134-139 27306439-3 2016 In this study, we explored whether a potential anti-fibrotic agent fluorofenidone (FD) exerts its anti-inflammatory and anti-fibrotic effects through suppressing activation of NACHT, LRR and PYD domains-containing protein 3 (NALP3) inflammasome and the IL-1beta/IL-1R1/MyD88/NF-kappaB pathway in vivo and in vitro. 5-methyl-1-(3-fluorophenyl)-2-(1H)-pyridone 67-81 myeloid differentiation primary response gene 88 Mus musculus 269-274