PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30515094-13 2018 Results: In vivo experiments confirmed that paeonol restricted atherosclerosis development and increased miR-223 expression, inhibited STAT3 pathway in ApoE-/- mice. paeonol 44-51 signal transducer and activator of transcription 3 Mus musculus 135-140 33442382-0 2020 Paeonol Suppresses Proliferation and Motility of Non-Small-Cell Lung Cancer Cells by Disrupting STAT3/NF-kappaB Signaling. paeonol 0-7 signal transducer and activator of transcription 3 Mus musculus 96-101 33442382-14 2020 In addition, paeonol inhibited the transcriptional activity of nuclear factor-kappaB (NF-kappaB) and phosphorylation of signal transducers and activators of transcription 3 (STAT3). paeonol 13-20 signal transducer and activator of transcription 3 Mus musculus 120-172 33442382-14 2020 In addition, paeonol inhibited the transcriptional activity of nuclear factor-kappaB (NF-kappaB) and phosphorylation of signal transducers and activators of transcription 3 (STAT3). paeonol 13-20 signal transducer and activator of transcription 3 Mus musculus 174-179 33442382-16 2020 Conclusion: Paeonol potently inhibited NSCLC cell growth, migration and invasion associated with disruption of STAT3 and NF-kappaB pathways, suggesting that it could be a promising anti-metastatic candidate for tumor chemotherapy. paeonol 12-19 signal transducer and activator of transcription 3 Mus musculus 111-116 26452780-0 2015 Paeonol inhibits B16F10 melanoma metastasis in vitro and in vivo via disrupting proinflammatory cytokines-mediated NF-kappaB and STAT3 pathways. paeonol 0-7 signal transducer and activator of transcription 3 Mus musculus 129-134 26452780-7 2015 In particular, paeonol disrupted both TNF-alpha-activated NF-kappaB and IL-6-activated STAT3 signaling pathways in B16F10 cells. paeonol 15-22 signal transducer and activator of transcription 3 Mus musculus 87-92 26452780-10 2015 Therefore, paeonol possessed antitumor activity in melanoma cells and mice model by interruption of the aggressive feedback through proinflammatory cytokines mediated NF-kappaB and STAT3 signaling activation. paeonol 11-18 signal transducer and activator of transcription 3 Mus musculus 181-186