PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35563976-9 2022 More than half of the human protein targets of xanthohumol with the highest docking scores have already been connected with the anticarcinogenic function, and four of them (including two important representatives of the matrix metalloproteinase family, MMP-2 and MMP-9) also have a known experimental correlation with xanthohumol. xanthohumol 47-58 matrix metallopeptidase 9 Homo sapiens 263-268 23562496-10 2013 Importantly, 2-hydroxychalcone and xanthohumol exerted more potent inhibitory effects on the proliferation, MMP-9 expression and invasive phenotype of MDA-MB-231 than chalcone. xanthohumol 35-46 matrix metallopeptidase 9 Homo sapiens 108-113 20447364-5 2010 Xanthohumol significantly inhibited elastase and MMP-9 activities from its lowest concentration, and MMP-1 and MMP-2 at its higher concentrations, which implies a greater protective effect on elastin. xanthohumol 0-11 matrix metallopeptidase 9 Homo sapiens 49-54