PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8279572-5 1993 Exposure of SP-A to peroxynitrite decreased its ability to cause lipid aggregation and to act synergistically with SP-B and SP-C in lowering surface tension of surfactant lipids. Peroxynitrous Acid 20-33 pulmonary surfactant-associated protein A Bos taurus 12-16 8279572-6 1993 Western blot analysis of SP-A exposed to peroxynitrite was consistent with fragmentation and polymerization of the 28- to 36-kDa triplet band, and amino acid analysis revealed the presence of significant levels of 3-nitro-L-tyrosine. Peroxynitrous Acid 41-54 pulmonary surfactant-associated protein A Bos taurus 25-29 8779998-9 1996 In addition, SP-A (1-3% by weight), treated with 0.25-0.5 mM TNM at pH 8, restored the surface-active properties of calf lung surfactant extract, previously damaged by exposure to peroxynitrite. Peroxynitrous Acid 180-193 pulmonary surfactant-associated protein A Bos taurus 13-17