PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30108910-7	2018	All the pyrone-based chalcones showed no recognizable level of cytotoxicity against normal human kidney cell line (HEK-293) up to 80 muM concentration and 11 exhibited an IC50 <= 100 muM (highest tested concentration).	Chalcones	21-30	latexin	Homo sapiens	186-189	
22854194-2	2012	The chalcones and flavanones were screened against mycobacterial FAS-II pathway using a recombinant mycobacterial strain, against which the most potent compound showed ~88% inhibition in bacterial growth and substantially induction of reporter gene activity at 100 muM concentration.	Chalcones	4-13	latexin	Homo sapiens	265-268	
31673309-7	2019	Screening of the whole chalcone library set led to the discovery of over 30 compounds, within six cancerous cell lines, possessing single digit muM IC50 activity as sole agents.	Chalcones	23-31	latexin	Homo sapiens	144-147	
25442306-2	2014	Among the synthesized chalcones, compound 6n was found to be the most potent and selective against A549 lung cancer cell line (IC50 = 0.8 muM).	Chalcones	22-31	latexin	Homo sapiens	138-141