PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27044026-2 2016 The inducible enzyme heme oxygenase-1 (HO-1) protects cells against inflammation and can be induced by electrophilic compounds like the chalcones (1,3-diphenylprop-2-enones) from the class of alpha,beta-unsaturated carbonyl compounds. Chalcones 136-145 heme oxygenase 1 Homo sapiens 39-43 19355962-6 2009 The anti-inflammatory activity of chalcones has been correlated with the induction of heme oxygenase-1 while phlorotannins have been found to inhibit matrix metalloproteinase, which is implicated in arthritis, chronic inflammation, and wrinkle formation. Chalcones 34-43 heme oxygenase 1 Homo sapiens 86-102