PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20667741-0	2010	Design, synthesis, and biological evaluation of prenylated chalcones as 5-LOX inhibitors.	Chalcones	59-68	arachidonate 5-lipoxygenase	Homo sapiens	72-77	
9871729-2	1998	In vitro, chalcones 2, 4, 8, 10 and 13 inhibited degranulation and 5-lipoxygenase in human neutrophils, whereas 11 behaved as scavenger of superoxide.	Chalcones	10-19	arachidonate 5-lipoxygenase	Homo sapiens	67-81	
31620227-0	2019	Chalcone-Thiazole Hybrids: Rational Design, Synthesis, and Lead Identification against 5-Lipoxygenase.	Chalcones	0-17	arachidonate 5-lipoxygenase	Homo sapiens	87-101	
20667741-5	2010	5-LOX in vitro inhibition assay showed higher potency of di-O-prenylated chalcones than their mono-O-prenylated chalcone analogs.	Chalcones	73-82	arachidonate 5-lipoxygenase	Homo sapiens	0-5	
12413856-0	2002	Development of 3D-QSAR models for 5-lipoxygenase antagonists: chalcones.	Chalcones	62-71	arachidonate 5-lipoxygenase	Homo sapiens	34-48	
12413856-2	2002	In order to identify the essential structural and physicochemical requirements in terms of common biophoric sites (pharmacophore) and secondary sites for binding and interacting with 5-lipoxygenase, a series of 51 compounds of chalcones has been used for the development of 3D-QSAR models on APEX-3D expert system.	Chalcones	227-236	arachidonate 5-lipoxygenase	Homo sapiens	183-197