PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29630947-5	2018	Mechanistically, inhibition of cancer cell invasion and inflammation by the compounds were mediated through suppression of the nuclear factor-kappaB (NF-kappaB) signaling pathway, which corroborated with the reported mechanism of action of chalcones.	Chalcones	240-249	nuclear factor kappa B subunit 1	Homo sapiens	127-148	
29630947-5	2018	Mechanistically, inhibition of cancer cell invasion and inflammation by the compounds were mediated through suppression of the nuclear factor-kappaB (NF-kappaB) signaling pathway, which corroborated with the reported mechanism of action of chalcones.	Chalcones	240-249	nuclear factor kappa B subunit 1	Homo sapiens	150-159	
30037040-8	2018	Among the pharmacological activities highlighted, anti-inflammatory activity was more evident than others, suggesting a multi-target Michael acceptor mechanism for the chalcones involving key regulators of the Nrf2 and nuclear factor- kappaB (NF-kappaB) pathways.	Chalcones	168-177	nuclear factor kappa B subunit 1	Homo sapiens	235-241	
30037040-8	2018	Among the pharmacological activities highlighted, anti-inflammatory activity was more evident than others, suggesting a multi-target Michael acceptor mechanism for the chalcones involving key regulators of the Nrf2 and nuclear factor- kappaB (NF-kappaB) pathways.	Chalcones	168-177	nuclear factor kappa B subunit 1	Homo sapiens	243-252	
26660296-0	2016	Design and Discovery of Some Novel Chalcones as Antioxidant and Anti-Inflammatory Agents via Attenuating NF-kappaB.	Chalcones	35-44	nuclear factor kappa B subunit 1	Homo sapiens	105-114	
25466202-2	2015	Emerging evidence indicates that various natural and synthetic chalcones exhibit antimetastatic activity through the inhibition of nuclear factor-kappaB (NF-kappaB), although the precise mechanism by which this occurs is currently unclear.	Chalcones	63-72	nuclear factor kappa B subunit 1	Homo sapiens	131-152	
25466202-2	2015	Emerging evidence indicates that various natural and synthetic chalcones exhibit antimetastatic activity through the inhibition of nuclear factor-kappaB (NF-kappaB), although the precise mechanism by which this occurs is currently unclear.	Chalcones	63-72	nuclear factor kappa B subunit 1	Homo sapiens	154-163	
22710558-0	2012	Natural chalcones as dual inhibitors of HDACs and NF-kappaB.	Chalcones	8-17	nuclear factor kappa B subunit 1	Homo sapiens	50-59	
22710558-14	2012	The dual inhibitory potential of the selected chalcones on NF-kappaB and HDACs was             investigated for the first time.	Chalcones	46-55	nuclear factor kappa B subunit 1	Homo sapiens	59-68	
18387817-9	2008	Specifically, flavonoids and chalcones regulate expression of VEGF, matrix metalloproteinases (MMPs), EGFR and inhibit NFkappaB, PI3-K/Akt, ERK1/2 signalling pathways, thereby causing strong antiangiogenic effects.	Chalcones	29-38	nuclear factor kappa B subunit 1	Homo sapiens	119-127