PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17458979-3 2007 However, polyphenols, except for procyanidin, in AP (i.e., catechins, chalcones, and phenol carboxylic acids) showed weak inhibitory activities on pancreatic lipase. Chalcones 70-79 pancreatic lipase Homo sapiens 147-164 32451094-6 2020 Furthermore, docking simulations indicated that two chalcones (isobavachalcone and bavachalcone) could interact with the key residues located in the catalytic cavity of PL via hydrogen binding and hydrophobic interactions. Chalcones 52-61 pancreatic lipase Homo sapiens 169-171 32451094-7 2020 Collectively, these finding provided solid evidence to support that Fructus Psoraleae contained bioactive compounds with lipid-lowering effects via targeting PL, and also suggested that the chalcones in Fructus Psoraleae could be used as ideal leading compounds to develop novel PL inhibitors. Chalcones 190-199 pancreatic lipase Homo sapiens 158-160 32451094-7 2020 Collectively, these finding provided solid evidence to support that Fructus Psoraleae contained bioactive compounds with lipid-lowering effects via targeting PL, and also suggested that the chalcones in Fructus Psoraleae could be used as ideal leading compounds to develop novel PL inhibitors. Chalcones 190-199 pancreatic lipase Homo sapiens 279-281